Cape Town City Center

Cape Town City Center

Moshi, Tanzania

Moshi, Tanzania

Amhara region, Ethiopia

Amhara region, Ethiopia

Arusha region, Tanzania

Arusha region, Tanzania

Amhara region, Ethiopia

Amhara region, Ethiopia

Manyara region, Tanzania

Manyara region, Tanzania

Amhara region, Ethiopia

Amhara region, Ethiopia

Arusha region, Tanzania

Arusha region, Tanzania

SeroSelectTB Project

The SeroSelectTB project has received generous support from the European and Developing Clinical Trials Partnership (EDCTP). EDCTP funds research addressing the prevention and treatment of poverty-related infectious diseases in sub-Saharan Africa. More information can be found on the EDCTP website.

In this project, the performance of a new triage test for active tuberculosis, SeroSelectTB, will be evaluated in multi-centre randomised controlled trials at health-posts in South Africa, Tanzania and Ethiopia. Cost-effectiveness evaluations will be conducted to support a value proposition to stakeholders and regulatory authorities, and to support commercialization requirements. 

Consenting adults will provide blood and saliva samples for screening by SeroSelectTB, and sputum collected for routine TB diagnosis by the health services. Clinical and sociodemographic information will be collected.

A reliable rapid test will make it possible to identify and selectively treat those with active TB at the local healthcare level. The expected impact includes accurate same-day diagnosis of patients with active TB, reduction of diagnostic delay and TB transmission, and diagnostic cost-savings for patients and healthcare systems in high burden countries.

SeroSelectTB is a multinational project coordinated by the Norwegian Institute of Public Health (Oslo, Norway). Partners include Stellenbosch University and Lateral Flow Laboratories (South Africa), Kilimanjaro Christian Medical University College (Tanzania), Armauer Hansen Research Institute (Ethiopia), National Institute for Public Health and the Environment (Netherlands), InVivo Biotech Services GmbH (Germany), Aether Dynamics Consulting & Trading GmbH (Austria), and E-MEDDIA (France).

Please follow this link to the scientific abstract of the project.

The SeroSelectTB project is supported by:

The European & Developing Countries Clinical Trials Partnership (EDCTP)

Norwegian Institute of Public Health

European Union

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